Carcinoma of the Urethra and Periurethral Glands

Carcinoma of the urethra and periurethral glands click to access explanations in the original CAP template

This is additional protocol for biopsy specimen.

Gross core data elements:

- Procedure:
- Tumor site:
- Tumor size:

Microscopic descriptions:

- Tumor histology and immunohistochemical studies:

- Histologic type (WHO 5e):
- Histologic grade for urothelial carcinoima:
- Histologic grade for SCC or adenoCA:
+ Tumor configuration:	Papillary Solid/nodule Flat Ulcerated Cannot be determined Other (specify):
+ Lymphatic and / or Vascular Invasion:
- Perineural invasion:

- Tumor extension (Male, Urothelial carcinoma of penile and bulbomembranous urethra): Noninvasive papillary carcinoma Carcinoma in situ Tumor invades subepithelial connective tissue Tumor invades adjacent structures Tumor invades adjacent structures, corpus spongiosum Tumor invades adjacent structures, periurethral muscle Tumor invades adjacent structures, corpus cavernosum Tumor invades adjacent structures, bladder wall Tumor invades adjacent structures, rectum Tumor invades adjacent structures, other (specify):

- Tumor extension (Male, Urothelial carcinoma of the prostatic urethra): Carcinoma in situ, involvement of the prostatic urethra Carcinoma in situ, involvement of the prostatic ducts Tumor invades urethral subepithelial connective tissue immediately underlying the urothelium Tumor invades the prostatic stroma surrounding ducts either by direct extension from the urothelial surface or by invasion from prostatic ducts Tumor invades the periprostatic fat Tumor invades adjacent structures Tumor invades adjacent structures, extraprostatic invasion of the bladder wall Tumor invades adjacent structures, rectum Tumor invades adjacent structures, Other (specify):

- Tumor extension (female): Noninvasive papillary carcinoma Carcinoma in situ Tumor invades subepithelial connective tissue Tumor invades adjacent structure Tumor invades adjacent structures, periurethral muscle (fibromuscular and adipose tissue) Tumor invades adjacent structures, anterior vagina Tumor invades adjacent structures, bladder wall Tumor invades adjacent structures, rectum Tumor invades adjacent structures, other (specify):

Surgical margins:

- Proximal mucosal margin:
- Distal mucosal margin:
- Deep soft tissue margin:
- Other margin(s) (specify):

Regional lymph nodes:

- Number of regional lymph nodes examined:
- Number of lymph nodes involved:
- Extracapsular spread:
- Size of largest metastatic deposit (mm), specify site:
- Size of largest lymph node involved (mm), specify site:

Distant Metastasis: Not applicable Not identified Other (specify): Cannot be determined:

Pathologic Stage Classification (AJCC 8e):

- TNM Descriptors:	m (multiple primary) r (recurrent) y (post treatment)
- Primary tumor (pT) (for the male penile urethra and female urethra):
- Primary tumor (pT) (for prostatic urethra):
- Regional lymph nodes (pN):
- Distant metastasis (pM):

+ Additional pathologic findings:

Keratinizing squamous metaplasia Inflammation/regenerative changes Metaplasia (specify type): Urethritis cystica et glandularis Intestinal metaplasia

- Other (specify):

+ Associated epithelial lesions:

None identified Condyloma Squamous dysplasia (low, intermediate, high grade) Urothelial papilloma Urothelial papilloma, inverted type Papillary urothelial neoplasm, low malignant potential (PUNLMP) Urothelial proliferation of uncertain malignant potential Urothelial dysplasia Cannot be assessed (explain):

- Additional notes: