CA Pharynx

Cancers of the pharynx (oropharynx, hypopharynx and nasopharynx) click to access explanations in the original CAP template

Please also refer to H&N biomarker protocol (HeadNeckBiomarkers 2.2.0.0, Sep-2023) for possible ancillary testings.

Microscopic descriptions:

- Tumor histology and immunohistochemical studies:

- Oropharynx and hypopharynx CA:
- SCC and variants (WHO 5e) :	Squamous cell carcinoma, conventional (keratinizing) Squamous cell carcinoma, nonkeratinizing Adenosquamous carcinoma Basaloid squamous cell carcinoma Papillary squamous cell carcinoma Spindle cell squamous cell carcinoma Verrucous squamous cell carcinoma Lymphoepithelial carcinoma (non-NP)
- Nasopharynx CA:
- Minor salivary glands CA:
- Neuroendocrine carcinoma (WHO 5e):
- Other histologic type:
- Histologic grade:
- Grade/Intrinsic biologic potential:
+ Tumor extension:
- Lymphatic and/or vascular invasion:
- Perineural invasion:
- HPV status by p16 IHC:
- HPV PCR:
- EBV (EBER ISH):

Surgical margins:

- Surgical margins:

Lymph nodes examination:

- Number of regional lymph nodes examined:
- Number of lymph nodes involved:
- Extranodal extension (ENE) :
- Size of largest metastatic deposit (mm), specify site:
- Size of largest lymph node involved (mm), specify site:
- Laterality:

Distant Metastasis: Not applicable Not identified Non-regional lymph node(s) (specify): Lung (specify): Liver (specify): Bone (specify): Brain (specify): Other (specify): Cannot be determined:

Pathologic Stage Classification (AJCC 8e):

- TNM Descriptors:	m (multiple primary tumors) r (recurrent) y (post treatment)
- HPV +ve oropharynx carcinoma	- Primary tumor (pT):
	- Regional lymph nodes (pN):
- HPV -ve oropharynx carcinoma	- Primary tumor (pT):
	- Regional lymph nodes (pN):
- Nasopharynx carcinoma	- Primary tumor (pT):
	- Regional lymph nodes (pN):
- Hypopharynx carcinoma	- Primary tumor (pT):
	- Regional lymph nodes (pN):
- Distant metastasis (pM):

Pathologic Stage Classification (AJCC 8e) for mucosal melanoma:

- TNM Descriptors:	m (multiple primary tumors) r (recurrent) y (post treatment)
- Primary tumor (pT):
- Regional lymph nodes (pN):
- Distant metastasis (pM):

+ Additional pathologic findings:

Keratinizing dysplasia, mild Keratinizing dysplasia, moderate Keratinizing dysplasia, severe (carcinoma in situ) Nonkeratinizing dysplasia, mild Nonkeratinizing dysplasia, moderate Nonkeratinizing dysplasia, severe (carcinoma in situ) Inflammation (specify type): Squamous metaplasia Epithelial hyperplasia Colonization, fungal Colonization, bacterial

- Other (specify):

- Additional notes: