CA larynx

Cancers of the larynx click to access explanations in the original CAP template

** Please also refer to H&N biomarker protocol (HeadNeckBiomarkers 2.3.0.0, Apr-2026) for possible ancillary testings.

Microscopic descriptions:

- Tumor histology and immunohistochemical studies:

- SCC and variants (WHO 5e, 2022) :	Squamous cell carcinoma, conventional (keratinizing) Squamous cell carcinoma, nonkeratinizing Adenosquamous carcinoma Basaloid squamous cell carcinoma Papillary squamous cell carcinoma Spindle cell [sarcomatoid] squamous carcinoma Verrucous squamous cell carcinoma Carcinoma cuniculatum Lymphoepithelial carcinoma (non-nasopharyngeal)
- Neuroendocrine carcinoma :
- Other histologic type :
- Histologic grade:
- Tumor extent:
- Lymphatic and/or Vascular Invasion:
- Perineural invasion:

Surgical margins:

- Invasive components:
- High grade dysplasia:
- Tumor bed margin :

** Please also refer to additional specimens and frozen sections for margin status.

Lymph nodes examination:

- Number of regional lymph nodes examined:
- Number of lymph nodes involved:
- Extranodal extension (ENE) :
- Size of largest metastatic deposit (mm), specify site:
- Size of largest lymph node involved (mm), specify site:
- Laterality:

** Please include also intraparotid and periparotid lymph nodes, in addition to the lymph nodes of the neck dissections.

Distant Metastasis: Not applicable Not identified Non-regional lymph node(s) (specify): Lung (specify): Liver (specify): Bone (specify): Brain (specify): Other (specify): Cannot be determined:

Pathologic Stage Classification (AJCC 8e):

+ Modified classification:	r (recurrent) y (post-neoadjuvant therapy)
- Primary tumor (pT) (for supraglottis):
- Primary tumor (pT) (for glottis):
- Primary tumor (pT) (for subglottis):
+ T suffix:	m (multiple primary tumors)
- Regional lymph nodes (pN):
- Distant metastasis (pM):

- Additional notes: