Colorectal Cancers

Cancers of the colon and rectum

There is a different protocol for biopsy specimen

There is a protocol for biomarkers

Microscopic descriptions:

- Tumor histology and immunohistochemical studies:

- Histologic type (WHO 2019):
- Histologic grade:
- Tumor extension:
- Sub-mucosal Invasion (pT1 only):	Depth of Sub-mucosal Invasion
- Sub-mucosal Invasion (pT1 only):	Extent of Sub-mucosal Invasion
- Macroscopic Tumor Perforation:
- Lymphatic and / or Vascular Invasion:
- Perineural invasion:
+ Tumor budding (ITBCC 2016): Number of tumor buds in one hot spot (0.785 mm2) (count buds in one x20 field, 22 mm eye-piece, divided by 1.21)

+ Type of polyp in which invasive carcinoma arose:
- Tumor deposits:
- Treatment effect (modified Ryan, 2005):

- Proximal margin:
- Distal margin:
- Radial or mesenteric margin:
- Other margin(s) (specify: ):
+ Status of non-invasive tumor at margin(s):

- Number of regional lymph nodes examined (including apical LN):
- Number of lymph nodes involved (including apical LN):
- Number of apical lymph nodes examined:
- Number of apical lymph nodes involved:
- Extranodal extension:
- Size of largest metastatic deposit (mm), specify site:
- Size of largest lymph node involved (mm), specify site:

Distant Metastasis: Not applicable Not identified Non-regional lymph node(s) (specify): Liver (specify): Other (specify): Cannot be determined:

- TNM Descriptors:	m (multiple primary tumors) r (recurrent) y (post treatment)
- Primary tumor (pT):
- Regional lymph nodes (pN):
- Distant metastasis (pM):

+ Additional pathologic findings:

Adenoma(s) Ulcerative colitis Crohn disease Diverticulosis Dysplasia arising in inflammatory bowel disease Other polyps (type[s]):

- Other (specify):

- Additional notes: