Appendix cancers

Carcinoma of the Appendix click to access explanations in the original CAP template

Microscopic descriptions:

- Tumor histology and immunohistochemical studies:

- Histologic type (WHO 2019):
- Histologic grade:
- Lymphatic and/on vascular invasion:
+ Perineural invasion:
- Tumor deposits:

- Tumor extension: Tumor invades lamina propria or muscularis mucosa Acellular mucin invades submucosa Tumor invades submucosa Acellular mucin invades muscularis propria Tumor invades muscularis propria Acellular mucin invades subserosa or mesoappendix but does not extend to the serosal surface Tumor invades through the muscularis propria into the subserosa or mesoappendix but does not extend to the serosal surface Acellular mucin invades the visceral peritoneum (serosa) Tumor invades the visceral peritoneum (serosa) Tumor directly invades adjacent organs or structures (specify): Cannot be determined: No evidence of primary tumor

Surgical margins for surgical specimens:

- Proximal margin: Cannot be assessed Uninvolved by invasive carcinoma, specifiy distance (mm): Involved by invasive carcinoma Involved by high-grade dysplasia Uninvolved by appendiceal mucinous neoplasm, specifiy distance (mm): Involved by low-grade appendiceal mucinous neoplasm Involved by high-grade appendiceal mucinous neoplasm Involved by acellular mucin

- Mesenteric margin: Cannot be assessed Uninvolved by invasive carcinoma, specifiy distance (mm): Involved by invasive carcinoma Involved by high-grade dysplasia Uninvolved by appendiceal mucinous neoplasm, specifiy distance (mm): Involved by low-grade appendiceal mucinous neoplasm Involved by high-grade appendiceal mucinous neoplasm Involved by acellular mucin

- Other margin(s) (specify: ): Cannot be assessed Uninvolved by invasive carcinoma, specifiy distance (mm): Involved by invasive carcinoma Involved by high-grade dysplasia Uninvolved by appendiceal mucinous neoplasm, specifiy distance (mm): Involved by low-grade appendiceal mucinous neoplasm Involved by high-grade appendiceal mucinous neoplasm Involved by acellular mucin

Lymph nodes examination:

- Number of regional lymph nodes examined:
- Number of regional lymph nodes involved:
- Extranodal extension:
- Size of largest metastatic deposit (mm), specify site:
- Size of largest lymph node involved (mm), specify site:

Distant Metastasis: Not applicable Not identified Non-regional lymph node(s) (specify): Intraperitoneal acellular mucin without identifiable tumor cells in the disseminated peritoneal mucinous deposits (specify): Intraperitoneal metastasis only (including peritoneal mucinous deposits containing tumor cells) (specify): Lung (specify): Liver (specify): Site(s) other than peritoneum (specify): Cannot be determined:

Pathologic Stage Classification (AJCC 9e):

- TNM Descriptors:	m (multiple primary tumors) r (recurrent) y (post treatment)
- Primary tumor (pT):
- Regional lymph nodes (pN):
- Distant metastasis (pM):

Acellular mucin or mucinous epithelium may invade into the muscularis propria. (T1 and T2 are not applicable to LAMN; Acellular mucin or mucinous epithelium that extends into the subserosa or serosa should be classified as T3 or T4a, respectively.)

+ Additional pathologic findings:

Appendicitis Perforation, not at tumor Ulcerative colitis Crohn disease Diverticulosis Sessile serrated lesion / adenoma / polyp

- Other (specify):

- Additional notes: