Stomach neuroendocrine tumor
Microscopic descriptions:
- Tumor histology and immunohistochemical studies:
-
Histologic type and grade (WHO 5e)
:
Using 22 mm eyepiece at x40 objective, counting 42 fields = 10 mm
2
. Divide by 5 to get hot spot mitotic count of 2 mm
2
G1: Well-differentiated neuroendocrine tumor (mitosis < 2, Ki67 < 3)
G2: Well-differentiated neuroendocrine tumor (mitosis 2-20, Ki67 3-20)
G3: Well-differentiated neuroendocrine tumor (mitosis > 20, Ki67 > 20)
Other (specify):
GX:Grade cannot be assessed:
Not applicable
-
Mitotic count
:
< 2 mitoses/2 mm2
2 to 20 mitoses/2 mm2 (specify: )
> 20 mitoses per 2 mm2 (specify: )
Cannot be determined (explain):
Not applicable
-
Ki-67 labeling index
:
< 3%
3% to 20% (specify: )
>20% (specify: )
Cannot be determined (explain):
Not applicable
-
Tumor size
:
Greatest dimension (mm):
All dimensions (mm x mm x mm):
Cannot be determined (explain):
- Tumor focality:
Unifocal
Multifocal (specify number of tumors):
Cannot be determined (explain):
- Tumor extension:
No evidence of primary tumor
Tumor invades the lamina propria
Tumor invades the submucosa
Tumor invades the muscularis propria
Tumor invades through the muscularis propria into subserosal tissue without penetration of overlying serosa
Tumor penetrates visceral peritoneum (serosa)
Tumor directly invades other organs or adjacent structures (specify):
Cannot be assessed
- Lymphatic and / or Vascular Invasion:
Not identified
Present
Cannot be determined
+ Perineural invasion:
Not identified
Present
Cannot be determined
For endoscopic resections:
- Deep margin:
Cannot be assessed
Uninvolved by tumor
Involved by tumor
- Mucosal margin:
Cannot be assessed
Uninvolved by tumor
Involved by tumor
- Other margin(s) (specify: ):
Cannot be assessed
Uninvolved by tumor
Involved by tumor
For gastrectomy specimens:
- Proximal margin:
Cannot be assessed
Uninvolved by tumor
Involved by tumor
- Distal margin:
Cannot be assessed
Uninvolved by tumor
Involved by tumor
- Omental (radial) margin:
Cannot be assessed
Uninvolved by tumor
Involved by tumor
- Other margin(s) (specify: ):
Cannot be assessed
Uninvolved by tumor
Involved by tumor
Regional lymph nodes:
- Number of regional lymph nodes examined:
- Number of lymph nodes involved:
+ Extranodal extension:
Not identified
Present
Cannot be determined
Distant Metastasis:
Not applicable
Not identified
Non-regional lymph node(s) (specify):
Lung (specify):
Liver (specify):
Bone (specify):
Peritoneum (specify):
Ovary (specify):
Other (specify):
Cannot be determined:
Pathologic Stage Classification (AJCC 9e)
:
- TNM Descriptors:
m (multiple primary tumors)
r (recurrent)
y (post treatment)
- Primary tumor (pT):
pT not assigned (cannot be determined based on available pathological information)
pT0: No evidence of primary tumor
pT1: Invades the lamina propria or submucosa and less than or equal to 1 cm in size
pT2: Invades the muscularis propria or greater than 1 cm in size
pT3: Invades through the muscularis propria into subserosal tissue without penetration of overlying serosa
pT4: Invades visceral peritoneum (serosa) or other organs or adjacent structures
- Regional lymph nodes (pN):
pN not assigned (no nodes submitted or found)
pN not assigned (cannot be determined based on available pathological information)
pN0: No regional lymph node metastasis
pN1: Regional lymph node metastasis
- Distant metastasis (pM):
Not applicable - pM cannot be determined from the submitted specimen(s)
pM1 (subcategory cannot be determined)
pM1a: Microscopic confirmation of metastasis confined to liver
pM1b: Microscopic confirmation of metastasis in at least one extrahepatic site
pM1c: Microscopic confirmation of both hepatic and extrahepatic metastases
+ Additional pathologic findings:
Atrophic gastritis
Intestinal metaplasia of gastric mucosa
Glandular dysplasia of gastric mucosa
Endocrine cell hyperplasia
Absence of parietal cells
Tumor necrosis
- Other (specify):
- Additional notes:
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