PD-L1 immunohistochemistry test FDA approved therapy (05-June-2020)

Immuno-oncology trends can be followed through portals in Cancer Research Institute (New York), Keytruda: pathologist centre and staining examples in lung cancers can be found in the IASLC Color Atlas.

Tumors Positive
Lung Cancers High: TPS>=50%
Low: TPS 1-49%
H&N SCC CPS>=1
Esophagus/EGJ carcinoma CPS>=1
Cervical Cancers CPS>=1
Triple Negative Breast Cancer CPS>=10

(with membrane signals > or = 1+ among 100 tumor cells)
(any types of signals > or = 1+)
- Positive immune cells among immune cells (%) :

PD-L1 calculator
DOWNLOAD AN EXCEL FILE

Risk assessment (from Keytruda website, 14-Aug-2024)